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Muscle spasms are generally self-limited to 2-4 weeks in length, with corresponding muscle relaxant treatment options reflecting acute duration of use


Nonspecific, low back pain is a predominant manifestation of muscle spasm, and in

most cases, has no underlying cause


Nonpharmacologic treatment is first recommended for muscle spasm relief, followed by nonsteroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen), muscle relaxants, and/or diazepam or botulinum toxin in refractory cases


3. Deyo RA, Weinstein JN. N Engl J Med 2001; 344:363.  4. Chou R. In the clinic. Ann Intern Med 2014; 160:ITC6.  5. Crit Rev Phys Rehabil Med. 2013; 25(1-2): 11–22.

6. [Guideline] American Academy of Neurology.National Guideline Clearinghouse. Available at https://guideline.gov/summaries/summary/50220. Accessed: January 2, 2018.


1. Crow, WT, Willis, D. J Am Osteopath Assoc. 2009 Apr;109(4):229-33.  2. Dagenais S, Caro J, Haldeman S.Spine J. 2008 Jan-Feb;8(1):8-20.