The United States has the opportuntiy to benefit

from tolperisone,

a treatment that has provided relief for millions in parts of Europe and Asia. 

Tolperisone is a medicine widely prescribed outside of the U.S. for acute muscle spasms and spasticity.  In the U.S., tolperisone is being investigated as a novel, non-opioid treatment for acute and painful muscle spasms without drowsiness or impact on cognitive function. Tolperisone is predicted to have analgesic activity in addition to muscle relaxation because of its centrally-acting dual voltage gated calcium and sodium channel blocker mechanism of action.  

Composition of matter and process patents have been issued by the US Patent and Trademark Office (USPTO) providing Orange Book listable patent protection through 2032.

 

TOLPERISONE  DATA

 

NO IMPACT ON COGNITION WITH TOLPERISONE

In a simulated driving

study, tolperisone performed similar to placebo and with less impairment than cyclobenzaprine

 

No binding activity directed to benzodiazepine receptor

No opioid binding activity; no abuse potential

The exact mechanism of action of tolperisone is not fully understood

DUAL MECHANISM FOR MUSCLE SPASM & PAIN RELIEF

Sodium AND Calcium Bocking Mechanism

 
 

CONTACT NEURANA

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Suite 860
San Diego, CA 92122
United States

contact@neuranapharma.com

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